I guess it depends how much of a 'typical woman' you are? Being practical, if you get a puncture, run flats will be less of an issue without a spare wheel, or cans of foam to hand.
I'm a newbie too with the MCS
, having just acquired one fitted with run flats, the ride is quite stiff, but not unbearable. Mine are also only 4 months old, so I will stick with them till I wear them down a bit, or my spine gives up.
How many mm of tread do you have left on you tyres currently?